Hearing Minos' comment, the two women on the opposite side of him in that carriage stopped talking for a moment as they reflected.
Someone really could not get all the impurities out of a spiritual pill, even if they were specially made for it.
Pills were combinations of different types of resources, such as medicines, the blood of spiritual beasts, some natural resources, such as the Spring of Life, which could also be used to produce pills.
And by merging each ingredient into a recipe, the alchemist would raise the potential set of those items, reaching a new level. If the ingredients separately could not make an individual, for example, jump from one step to another, this would become possible after refining done by that expert.