According to the records of Stall Literature, temperature control was the key in large-scale production of nitrifying glycerol because the excessive heat of exothermic reactions was extremely prone to cause the sensitive dynamites to explode. As long as the temperature of the large reaction vessel could be kept constant, the nitrating glycerin could be safely manufactured in batches.
However, the ice-water mixture had limited performance in heat absorption, especially when a large amount of heat was released. Its cooling rate was slow while the consumption of itself was fast. Besides,it was very troublesome to produce ice cubes. In light of these, ice cubes were suitable for laboratory tests, but not for the mass production. As the Frozen Coffin of Agatha could easily produce low temperatures, such as nearly 100 below zero, it was undoubtedly a great way to cool down the container.