All of Sid's attempts to break free from the array trap were futile. The mana poison soon entered his system because of the constant smoke released by the four vials.
Sid eventually got on his knees coughing a mouthful of blood. His mana circuits had gone haywire after consuming the poison. It resulted in him suffering multiple organ failures at the same time. The poison wouldn't have acted this way this fast. But the array trap enhanced the effects of the poison by modulating the mana inside it to favour the poison.
Eren had been studying the array traps ever since he got the book from the Purgatory's underground dungeon. Since the subject of the array was completely new for him, it took him a while to get the hang of the setup.
The butcher hadn't used anything like this in his previous timeline. So Layla had helped him from time to time in her own limited capacity whenever he had doubts.