Mental illness can be a major reason. Just like Andrea Yates who had postpartum depression and psychosis. These mental conditions can distort a person's perception of reality and lead to such tragic actions.
One of the most infamous cases is that of Mary Bell. In 1968 in the UK, she killed two young boys. She was a child herself at the time. Her actions were extremely shocking. There were speculations about her troubled upbringing which might have contributed to her actions. It was a very sad and disturbing case that left a mark on the community and in criminal history.
I'm not sure which specific 'kids killed story' you are referring to. There could be many such tragic stories around the world, perhaps in the context of accidents, crimes, or disasters.
There are many possibilities. In a story where kids are killed in a natural disaster, nature itself is sort of 'involved' but also rescue workers who may or may not be able to save them in time. In a criminal - related 'kids killed story', it could be the perpetrator, witnesses who might have not done enough to stop it, and the community that could have been more vigilant to prevent such a tragedy.
There are so many possible scenarios for the '2 moms 3 kids killed story'. Maybe it was related to a faulty building that collapsed, trapping and killing them. Another possibility is that they were involved in a situation where there was a lack of proper safety measures, such as a fire in a building without adequate fire escapes. Without more context, it's just speculation.
The story of Infamous 2 follows Cole MacGrath. He has powers and is on a journey to become more powerful to face new threats. He travels to a new city, New Marais, which is filled with all sorts of challenges. There are different factions in the city, some support him and some are against him. Cole has to make choices throughout the game that affect his powers and how the story unfolds.
I think it's more of a fictional creation. While some stories draw inspiration from real life, this one might have just taken a few concepts and built a fictional plot around them in 2020.
Most probably not. Usually, works labeled as 'Infamous' are fictional, crafted by the imagination of the creators rather than being rooted in real events.