Another possible motive is that Orochimaru sees Naruto as a potential powerful ally or tool. Naruto has shown great potential and growth throughout the series. Orochimaru could think that by taking Naruto and molding him in his own way, he could have a powerful weapon at his disposal. He might also want to use Naruto to get back at Konoha in some way, since Naruto is one of Konoha's most important assets.
One possible motive could be the pursuit of power. Orochimaru is known for his vast knowledge of jutsu. Naruto might think that by joining him, he can gain the strength needed to protect his village better or to bring Sasuke back more effectively.
One possible motive could be to change Orochimaru's evil ways. Naruto might think that by changing Orochimaru's gender, he can disrupt Orochimaru's identity and power structure. Since Orochimaru is so used to being male and having a certain way of doing things, being female could throw him off balance.
A possible plotline could be Orochimaru's redemption. He realizes the error of his ways and joins Naruto in protecting the ninja world. He could use his vast knowledge of jutsu and forbidden arts to help Naruto against new threats.
One possible reason could be in the realm of artistic interpretation in the fanfiction. The author might want to explore a different aesthetic or a unique plot where Naruto has some physical or behavioral traits similar to Orochimaru for shock value or to create a new kind of character dynamic.
They could be related as adversaries with a strange connection. In fanfiction, Orochimaru might be after Naruto not just for the Nine - Tails, but also because Naruto has something that Orochimaru lost long ago. This creates a complex dynamic where they are constantly at odds, but there is also a deeper underlying connection.
One possible motive could be revenge. Maybe the oc or someone close to the oc has been wronged by Danzo in the past. So, to seek justice, the oc decides to take him down.
The sense of isolation could be a motive. If Naruto never truly felt accepted in Konoha despite his efforts, he might snap. He's always wanted to be recognized, but if that never fully happens, he could turn on the village. For example, if he's constantly passed over for important missions or not given the respect he thinks he deserves as a powerful ninja.
The overall theme of the fanfiction could change. If Naruto absorbs Orochimaru, the story could start to explore themes like the nature of power and corruption more deeply. It might also delve into how Naruto can use Orochimaru's power for good, rather than succumbing to the evil associated with it. This could make the fanfiction more of a moral exploration within the Naruto universe.
Perhaps Naruto starts to have a connection to Orochimaru's other experiments or creations. He might find himself in a situation where he has to either help or fight these other 'products' of Orochimaru's mad science. Also, the fanfiction could explore how Naruto's friends react to what has happened to him. Do they trust him still? Or are they afraid of what Orochimaru might have turned him into?
In this type of fanfiction, it might also be that Naruto joins Orochimaru to spy on him. The Hidden Leaf Village realizes they need to know Orochimaru's plans from the inside. Naruto, being the brave and somewhat reckless one, volunteers for the mission. He endures Orochimaru's experiments and teachings while secretly sending information back to the village. Eventually, when the time is right, he betrays Orochimaru and uses the knowledge he gained against him.