Maybe the dragon has been enchanted by a dark wizard to specifically target Harry. Harry has to face this dragon alone and due to the dragon's enhanced abilities from the enchantment, he is unable to survive the encounter.
A possible plot could be that the dragon is a new, unknown and extremely powerful species. Harry is sent to investigate it but underestimates its power and gets killed.
Well, one possible plot could be a wizard who has picked up the Muggle habit of smoking cigarettes and how it affects his magic. Maybe his spells start to go awry because the smoke interferes with the magical energy. Another could be a group of Hogwarts students who discover cigarettes in the Forbidden Forest and have to deal with the consequences of this Muggle item in a magical place. But these are just very speculative ideas as it's not a common type of fanfiction.
Perhaps there's a fanfiction where Ron is forced to work at a dentist's office as a punishment. He has to deal with all kinds of strange patients, from veelas with very sharp teeth to giants with massive molars. His misadventures in the dentist office, trying to use magic to get out of his work or accidentally making things worse, could make for a really funny and engaging plot.
Another plot could involve time - travel gone wrong. Marinette tries to go back in time to fix a major mistake, but something disrupts the time - space continuum and she gets caught in a loop that ultimately leads to her death.
There are also fanfics with a plot where Harry discovers a lost dragon species that has special powers related to time or space. This discovery leads him on a journey to understand these powers and how they can be used to rewrite the history of the wizarding world, or perhaps even prevent some of the tragedies that have occurred in the past. It's a very creative and engaging plot idea that takes the Harry Potter universe in a new direction.
One possible plot could be Harry trying to understand Voldemort's past and motives through the letters. Maybe he writes to ask about Voldemort's childhood, what led him to become so evil. Another could be Harry attempting to persuade Voldemort to change his ways, using the letters as a form of communication to reach the dark wizard's humanity. Or perhaps Harry writes to taunt Voldemort, using the fanfiction as a way to get under his skin and make him angry in a psychological battle.
One possible plot is that Harry discovers a hidden prophecy that says only by helping Voldemort can he truly save the wizarding world in the long run. So, he reluctantly starts to assist Voldemort in his conquests, all while secretly planning to turn the tables.
A possible plot could be Faith Lehane getting sorted into a Hogwarts house. It would be interesting to see which house she'd fit into, whether it's the brave Gryffindor or the cunning Slytherin. Her character traits would likely influence how she interacts with her housemates and professors.
A tragic ending could be that Harry's death leads to the fall of the good side in the wizarding war. His friends, demoralized by his loss, are unable to fight back effectively against the dark forces.
A fanfic might also have a plot where Garlic Jr. makes a deal with a more powerful villain from another dimension. However, the deal backfires on him. The other villain double - crosses him during a battle with the Z - Fighters. This leaves Garlic Jr. vulnerable, and he is quickly dispatched by Goku or one of the other heroes.
One possible plot development could be that Hermione is left with a deep sense of guilt and responsibility. She might then take on Harry's mission or cause in his memory. For example, if they were fighting against a new dark wizard, Hermione could become even more determined to defeat the enemy.