Well, it could start with some sort of time - travel or alternate universe situation. Maybe Fem Naruto from another dimension ends up in a world where she has to take on the role of Sasuke's mom. She would have to deal with Sasuke's family history and the Uchiha clan drama, all while having her own Naruto - like personality traits. It would be a really interesting mix of her being a strong - willed and determined mother figure, but also having that goofy Naruto charm.
I'm not sure if there is such a specific fanfic. There are countless Naruto fanfictions out there, and while the idea of Fem Naruto being Sasuke's mom is quite an unusual and creative concept, it may or may not exist. You could try searching on popular fanfic websites like Fanfiction.net or Archive of Our Own to see if you can find one.
One possible plot could be that fem - Naruto, as Sasuke's big sis, is very protective of him. She might try to keep him from going down the dark path he did in the original series. Maybe she uses her own ninja skills and her strong - willed personality to guide Sasuke and make sure he stays on the right track.
One possible plot could be that in this fanfiction, Sasuke finds a female Naruto in a weakened or some special state and decides to take her in as a pet. Maybe Naruto has lost her memories and Sasuke, out of some complex feelings like protectiveness or curiosity, keeps her around. He might train her like a pet at first, but as time goes on, their relationship could start to change and develop into something more complex and deep.
One possible reason could be competition. Maybe in this fanfic, they are competing for something like recognition in the ninja world. Naruto, as a female, might feel that Sasuke is getting more attention or opportunities, which makes her jealous and eventually turns into hatred.
Perhaps they leave because they discover a new threat that the ninja villages are not taking seriously. Naruto and Sasuke decide to take matters into their own hands. They travel to different places, gathering information and allies. Their relationship also evolves during this time, from just comrades to true brothers who understand each other completely.
Well, perhaps in the fanfiction, Fem Sasuke's blindness is a result of some dark jutsu. Naruto, with his determination, tries to find a way to restore her sight. Along the way, they encounter many old foes and new allies. The story could explore how Fem Sasuke copes with her new disability and how it changes her ninja skills, for example, she might develop new ways of using her Sharingan even without sight.
The plot might involve Naruto with the Rinnegan being a bit of an outcast in the village at first because of the strange and powerful new dojutsu. Fem Sasuke could be the one to understand him and encourage him to embrace it. They could then go on a quest to discover the origins of the Rinnegan together, facing various challenges along the way, like ancient ninja traps and powerful, long - forgotten clans.
Maybe in the fanfic, a dark force is trying to corrupt Sasuke's Sharingan. Sasuke, realizing he can't control it on his own, gives it to Naruto. Naruto, with his strong will, battles the dark influence within the Sharingan. He uses his own positive energy and friendship bonds to purify the Sharingan. Eventually, he masters it and uses it to bring light back to the ninja world, also using it to reunite with Sasuke in a more powerful and united way.
One possible reason could be that it goes against the original dynamic between Naruto and Sasuke. In the original story, their relationship is based on a deep male - male bond of rivalry and friendship. Changing Sasuke to a female might disrupt that established connection.
The story might revolve around the son's relationships. He could have a special bond with his mother, Fem Naruto, learning from her about perseverance and kindness. With Sasuke as his father, he may inherit a sense of mystery and a drive for justice. His friends could be a diverse group, some from noble ninja families and others from more common backgrounds. Their influence on him could shape his character and decisions throughout the fanfic.