The Vampires were arrogant and preferred to attack only with themselves, not focusing on teamwork. On the other hand, the Werewolves were a pack. They didn't have the arrogance. They were like a massive family who knew how to fight together, and that's what made them so hard to deal with.
Even worse was the effect of their attacks. Vampires used their teeth to suck the blood of their targets, while the Werewolves used their fangs to inject poison into their targets. The poison was ineffective on an ordinary human, but it worked the best on the Vampires, making them weaker and even paralyzing after a sufficient amount of venom was injected. That's what made the Werewolves so dangerous to face. They were like the natural enemies of the Vampires.
That's also why despite there being more Vampires in the world than the wolves, the Werewolf Kingdom was still completely intact.