Grimm's experiment that required him to look for materials that carried Destructive Energy needed to be carried out one part after another.
Basic materials, basic energy, complex synthetic materials, complex synthetic energy, undocumented unknown materials, exotic energy, mystical energy...
Among them, both the basic materials and basic energy were the simplest parts.
Even so, Grimm's basic material filtering experiment went on for decades before his expedition to the Infernal Spirit World!
The number of complex synthetic materials was thousands or tens of thousands of times as many as that of basic materials. If he wanted to complete all the experiments, did that represent tens of thousands or hundreds of thousands of years?
Not to mention the complex synthetic energy as well...