Most fifth-order Monster Beasts can withstand Sky-Reaching Spiritual Treasures; the difference is just a matter of how much they can resist. Even the toughest tortoise shell can be broken—it's a question of time.
Fifth-order Flood Dragons can also resist Sky-Reaching Spiritual Treasures. However, after successfully cultivating the first layer of the Heavenly Demon True Scripture, in addition to resisting Sky-Reaching Spiritual Treasures, Shen Long has a suppressive effect on Monster Beasts below the fifth order. As his Cultivation increases, he can even suppress fifth-order Monster Beasts.
According to the texts, the higher the Cultivation, the stronger the suppression.
The Heavenly Ape Transformation cultivated to the thirteenth layer, one of the three Sect Protecting Techniques of the Spirit Control Sect, allows one to resist Sky-Reaching Spiritual Treasures and transform into a fifth-order Demon Ape, employing some of the Divine Skills of the fifth-order Demon Ape.