Well, unfortunately, Spike does meet his end in the Cowboy Bebop manga. It's a bittersweet moment that leaves a lasting impression. The way his death is depicted shows the intensity and seriousness of the story.
Cowboy Bebop was not based on a manga. It was created directly as an anime with its own unique story and style. The anime gained popularity for its compelling characters and plot.
One of the great ones is 'A New Dawn for Spike and Faye'. It really captures their complex relationship. The author does an amazing job of showing how they both have their own demons but still find a connection in the chaos of the Bebop universe.