Saitama is a very powerful hero in the One Punch Man universe. He can defeat any opponent with just one punch. He has a simple appearance and a somewhat laid - back personality.
He could interact with Tsukune, the main human character in the Yokai Academy setting. They might share their experiences of being different in their respective worlds.
Genos could be an unexpected opponent. He might be forced to fight Saitama due to some mind - control or a misunderstanding in the rules of the tournament. It would be really interesting to see how Saitama would handle fighting his own disciple, and how Genos would fare against his master's incredible strength.
The villains would have a mixed reaction. Some of the more power - hungry ones might see this as an opportunity to join forces with Saitama and cause even more chaos. However, there would also be villains who are afraid of Saitama's power, even if he's on their side now. They would be worried that he could turn on them at any moment. Overall, Saitama turning evil would completely disrupt the existing power dynamics in the One Punch Man world.
Well, Saitama All Fiction could potentially refer to a fan - created idea that emphasizes Saitama's ability to be above all the normal rules of the fictional One Punch Man universe. For example, his strength is so overwhelming that it's like he exists in a realm of his own, where the typical limitations of the story don't really apply to him. He can defeat any foe with just one punch, and this 'All Fiction' concept might be an attempt to explain how and why he's so powerful in such a ridiculous way.