In a 'Girl vs Monster' fanfic, the girl could be from a long line of monster hunters. She is the only one left in her family though. The monster she's up against is the one that killed her family. This adds an emotional depth to the story as she not only fights for survival but also for revenge. She might use her family's secret techniques to take on the monster.
Definitely. The comic version of Homelander is portrayed as having greater strength and capabilities. This is evident in his confrontations and the scale of his power displays throughout the comic series.