Sure is. Deadpool originated as a comic book character and has had many storylines and adventures in that medium. The comic version is what made him so famous.
Well, Deadpool's origin story in the comic book starts with Wade Wilson. He was a guy with a rough life. When he got cancer, he volunteered for this secret experiment. This experiment was not what he expected. They basically tortured him and mutated his cells. As a result, he got his unique look and powers. His healing factor is really strong, which is a big part of who he is now. And his mind got a bit jumbled too, which is why he's so unpredictable.