Sure. Thor and Hercules have clashed multiple times in different comic series. Their fights often stem from differences in power, ideology, or the circumstances of the story.
Thor would have a good chance of winning. His powers are not only physical but also magical. He can summon lightning storms and has the ability to heal himself. Darth Vader, while a formidable opponent with his dark side powers and lightsaber skills, is still mortal. Thor could withstand a lot of damage and keep coming back at Vader. Also, Thor's hammer can only be lifted by those worthy, which gives him an added layer of protection. If Vader were to try and grab the hammer, he would not be able to, and Thor could use that moment to strike.
Well, if we consider Batman, he doesn't have superpowers like Thor or most of the Justice League members. But he's a brilliant strategist. In a fight against Thor, he might use his gadgets and knowledge of Thor's weaknesses (if he found any) to try and win. However, Thor's raw power is a huge factor. On the other hand, against the entire Justice League, Thor would have to be very strategic himself. He could target the more vulnerable members first, like Flash who might be caught off - guard by Thor's attacks. But the combined powers of the Justice League could overwhelm him.
It's really hard to say. Thor has superhuman strength and can control lightning. But Harry Potter has a whole arsenal of spells. If Harry could manage to disarm Thor quickly with Expelliarmus, he might have a chance. However, Thor's physical power is no joke. One swing of his hammer could cause a lot of damage.