In some fanfictions, when Luffy gets sick, his crewmates go into a frenzy. Nami might be the first to try and find a cure, using her knowledge of the sea and islands. Zoro would probably stand guard, ready to protect Luffy from any potential threats while he's weak. And Chopper, of course, would be the main doctor, frantically trying different medicines and treatments he has learned. It often makes for an interesting plot as it shows the crew's strong bond and how they handle a situation where their usually indomitable captain is down.
The characters' reactions can be quite diverse. Chopper would be extremely worried and immediately start his medical examination. He'd be constantly checking Luffy's symptoms and trying different remedies. Nami would be worried too but also thinking about how this could affect their journey and the crew's safety. Zoro might seem nonchalant on the outside but would be secretly on high alert, ready to fight off any danger. Sanji would cook up all kinds of nutritious food to help Luffy get better.
In addition to his family and friends, the medical ninja in the village would be involved. They would be the ones to accurately diagnose Boruto's condition. Shizune, for example, could come and check on him, using her vast medical knowledge. And the other young medical ninjas might learn from this case, as Boruto's illness could be something new or unusual, so they would be eager to assist and gain experience while taking care of him.
Rayleigh would be a great candidate. He's an experienced pirate and has already trained Luffy for a while. He has a lot of knowledge about the world of pirates and could give Luffy a talk about the deeper secrets of the Grand Line or how to deal with the powerful enemies that lie ahead.
Her best friend Veronica would probably be one of the first to help. Veronica is wealthy and could use her resources to get the best doctors for Betty.
Seth could be the one to help her. As her brother, he would be very concerned and might use his own knowledge of Fablehaven and its secrets to try and find a cure. He could also enlist the help of some of the friendly magical creatures they've befriended, like the fairies or the satyrs.
Obviously, her best friends Sam and Freddie would visit her. They are always there for each other. Maybe Gibby would also come over with his unique brand of humor to try and cheer Carly up.
His teammates, Sasuke and Sakura, would surely be involved. Sasuke, although he may not show it as much, still cares about Naruto. He would keep an eye on Naruto's condition, and if there was any sign of danger, he would be ready to protect him. Sakura would be more hands - on with the medical care, checking his temperature, giving him medicine, and making sure he rests properly.
Sango could also take care of Kagome. As a strong and kind - hearted woman, she would know how to nurse Kagome back to health. She might use her knowledge of herbs and remedies to make Kagome feel better. Plus, she would offer emotional support to Kagome during her illness.
It could be about Luffy having an important conversation. Maybe it's about his dreams, his crew, or some kind of revelation he has. Without reading it, it's hard to say exactly.