Madara Uchiha could be the cause. Even if he's dead, his influence could still be around. Maybe he left behind some sort of genjutsu or curse that affects Naruto's mind and drives him crazy. After all, Madara was always planning something big and Naruto would be a great pawn if he's out of control.
Sukuna does die in the manga. The way it happens is quite dramatic and ties in with many other elements of the story, adding depth and tension to the overall narrative.
No. Ryomen Sukuna is a fictional character from Japanese mythology and modern manga/anime. He doesn't have a basis in a true historical event or person.
Nope. Ryomen Sukuna has no basis in reality. It's a product of the creative minds of the writers and illustrators who designed a captivating fictional character for the enjoyment of the audience.
Well, without more details it's hard to say exactly. It could be she was under the influence of something, like drugs or alcohol, which made her act in a crazy way on Caroline Street. Another possibility is that she had a sudden emotional outburst because of a traumatic event that she just experienced or remembered while on that street.