Oh, for sure! Thanos squared off against the Avengers multiple times in the comics. Their clashes were intense and had a huge impact on the comic universe.
The plot could involve the ghouls from Tokyo Ghoul being brought into the Avengers' world. Maybe the Avengers initially mistake the ghouls for new, dangerous threats. But as they learn more about the ghouls' situation, they might try to find a way to co - exist. For example, Kaneki could share his story with the Avengers, and they could be sympathetic. Then they could team up to fight a common enemy, like a new type of super - villain who wants to use the power of ghouls for evil purposes.
It could strengthen their relationships. When the Avengers watch Tony fight Thanos, they see his courage and determination. This might make them respect him more, especially those who had doubts about him before. For example, Clint Barton might see Tony in a new light and be more willing to work with him in future battles.
Well, in such a fanfiction scenario, the Avengers might initially struggle against Venom. Venom is extremely powerful and has a ferocious nature. However, the Avengers have the advantage of teamwork. For example, Black Widow could use her stealth and combat skills to distract Venom while Hulk smashes into him. And Doctor Strange could use his magic to try and separate Venom from his host if possible.
One possible reason could be moral conflicts. For example, if the fight involves harming innocent civilians, some Avengers might refuse. Another reason could be internal disagreements within the team. Maybe they don't trust the motives behind the fight or the leadership in that particular fanfic scenario. Also, they could be exhausted from previous battles and simply not in the physical or mental state to engage in another fight.
It's really hard to say who would win. The Avengers are a powerful team with diverse abilities, but Venom is no pushover. If the Avengers can work together well, they might have the upper hand. But if Venom manages to isolate and take down some of the Avengers one by one, he could win.
In this Avengers assemble dracula fanfic scenario, the Hulk might be a wild card. He could just smash Dracula without much thought. But Dracula is not an easy foe. He has centuries of combat experience. Black Widow and Hawkeye would also play important roles. Black Widow could use her combat skills and intelligence to find Dracula's lair and Hawkeye could shoot his arrows, perhaps ones with silver tips which are effective against vampires.
It could create a rift. Some Avengers might still believe in fighting, while others are firmly against it. For instance, Captain America, who has always been about duty and fighting for what's right, might be at odds with Iron Man, who could be more cynical after seeing the consequences of their actions. This would lead to a lot of internal conflict within the group.