Well, revenge can be seen as a theme too. There are characters who are seeking vengeance for past wrongs done to them or their loved ones. Also, the exploration of different forms of magic and power is a significant theme. The various characters possess different magical abilities, and how they use or are used by these powers is an important aspect of the story.
In general, the Dorohedoro anime is quite true to the manga. It captures the key elements and the unique style of the source material. Some small adjustments might be made for better visual presentation or to fit the animation format, but they don't deviate much from the manga's core.
The Dorohedoro anime ends approximately at a certain point in the manga, but it's not an exact one-to-one match. Some storylines might be slightly different or left out.
En is a very complex character. His power and his role in the world of Dorohedoro are quite fascinating. He has a certain arrogance, but also a vulnerability that you don't expect at first. Shin is also interesting. He's a bit of an enigma, always seeming to be in the middle of things and having his own motives that are not always clear. He's got a mysterious air about him that draws you in.
One idea could be a crossover with 'Fullmetal Alchemist'. Dorohedoro's dark and gritty world combined with the alchemical concepts would be fascinating. For example, the characters from Dorohedoro could be exposed to the laws of equivalent exchange. Another plot could involve a crossover with 'Hunter x Hunter'. The nen abilities in 'Hunter x Hunter' could interact in strange ways with the magic in Dorohedoro's world. Maybe a character from Dorohedoro has to participate in the Hunter Exam. A third idea is a crossover with 'Tokyo Ghoul'. The idea of the ghouls' existence in Dorohedoro's setting and how they would coexist or clash with the existing creatures and characters there.
In a Dorohedoro crossover with 'One Punch Man', Saitama would be an interesting addition. His overpowered nature would contrast with the often - more - gritty and complex power levels in Dorohedoro. Another good character could be Guts from 'Berserk'. His dark and brooding personality would fit well in Dorohedoro's gloomy atmosphere. Also, Edward Elric from 'Fullmetal Alchemist' could bring his knowledge of alchemy and his quest for truth to the Dorohedoro world.
The ending of a drama was usually a tragic ending because a drama was usually a work that expressed a serious theme. It needed to show that the protagonist experienced a series of setbacks and difficulties and finally failed to reveal the weakness of social reality and human nature. This kind of ending was even more shocking and made people feel deep sadness and reflection.
However, there were also some comedic endings, such as Andy and Xiao Bao in Ode to Joy. Although the ending was also a tragedy, it was expressed in a comedy way to make people feel sad, but at the same time, there was some relief and a sense of humor.
There are also some dramas that may end with unclear endings, such as the political struggle in House of Cards. Although the protagonists made some plans and strategies at the beginning, they became unclear at the end. It is not known whether the protagonists will succeed or not. This kind of ending may make people feel a little disappointed, but it also increases some suspense and attraction.