En is a very complex character. His power and his role in the world of Dorohedoro are quite fascinating. He has a certain arrogance, but also a vulnerability that you don't expect at first. Shin is also interesting. He's a bit of an enigma, always seeming to be in the middle of things and having his own motives that are not always clear. He's got a mysterious air about him that draws you in.
Well, revenge can be seen as a theme too. There are characters who are seeking vengeance for past wrongs done to them or their loved ones. Also, the exploration of different forms of magic and power is a significant theme. The various characters possess different magical abilities, and how they use or are used by these powers is an important aspect of the story.
In general, the Dorohedoro anime is quite true to the manga. It captures the key elements and the unique style of the source material. Some small adjustments might be made for better visual presentation or to fit the animation format, but they don't deviate much from the manga's core.
The Dorohedoro anime ends approximately at a certain point in the manga, but it's not an exact one-to-one match. Some storylines might be slightly different or left out.
In fiction, characters like Thor from the Marvel universe are very strong. He wields his enchanted hammer Mjolnir and has the power of lightning. He has faced many powerful enemies and held his own. Then there's Hulk. His strength increases as he gets angrier, and he can smash through just about anything. In the world of Middle - earth from Tolkien's works, Morgoth was an extremely powerful character in the lore, though he was ultimately defeated. But his power was such that he could cause great destruction and corruption.
One of the strongest characters in fiction is Superman. He has superhuman strength, can fly, and has heat vision among other powers. His abilities make him extremely formidable against almost any foe.
It really depends on the specific fictional universe. In superhero comics, characters like Superman and Thor are often considered among the strongest. But in fantasy worlds, maybe characters like Gandalf or Dumbledore take the lead.