Carly would probably be the first one to take care of Sam. They're best friends, after all. She'd bring her soup and make sure she has enough blankets.
One idea could be that Sam is kidnapped by a group of rogue hunters who think he's gone too far in his use of demon powers. They lock him in an abandoned bunker and try to 'exorcise' the 'demon' out of him, not realizing he's in control. His brother Dean has to race against time to find him, following a series of cryptic clues left by the kidnappers.
Perhaps Sam gets hurt while trying to protect a civilian. He jumps in front of a werewolf's attack meant for someone else. This would show his selfless nature. The local hunters in the area might not trust Sam and Dean at first, but seeing Sam's sacrifice could change their minds, adding an interesting dynamic to the story.
One possible plot development could be that his friends and family rally around him. They might search desperately for the person who shot him. For example, if it was a case of mistaken identity, they could start to dig into Sam's recent activities to find any leads. Maybe they discover that Sam was unknowingly involved in something dangerous, like being in the wrong place at the wrong time during a criminal deal. This could lead to a whole new sub - plot where they try to figure out who the real target was.
It could be a case of mistaken identity. Sam might look similar to someone else who is involved in some sort of illegal or dangerous activity. The real target's enemies could have thought Sam was him and shot him instead. In a fanfiction world, this could lead to all sorts of twists and turns as the characters try to figure out who the real target was and why they were being targeted.
Well, it depends on the type of fanfiction. In darker fanfictions, Sam getting shot could be the start of a downward spiral for the Winchester brothers. Dean could become overly consumed with revenge if it was a hunter or a monster that shot Sam. On the other hand, in more positive fanfictions, Sam getting shot could lead to a moment of self - discovery. He might realize how much he has to live for and how many people rely on him. Maybe it makes him reevaluate his relationships, like his bond with Dean or his friends in the hunting community.
In this fanfiction, perhaps Sam's sickness is something really unique that no one has ever seen before. It could be a magical or science - fictional kind of illness. Her friends could go on a wild adventure to find a cure, traveling to strange places and meeting all kinds of interesting characters along the way.
Well, Dean would probably go into full - on search - and - rescue mode. He'd start by reaching out to all their contacts in the hunter community. Maybe he'd call Bobby in spirit form if he could, asking for any leads or advice. He'd also check Sam's last known locations and look for any signs of a struggle.
Perhaps Sam gets hurt while trying to protect a civilian in Flashpoint. The civilian feels guilty and tries to help in his recovery. This could lead to an interesting bond between them. Meanwhile, Sam's team is investigating who was behind the attack on the civilian that led to Sam's injury, and they uncover a conspiracy within the Flashpoint society.
Often, the theme of family is central. Dean's reaction to Sam's psychic boost can vary from being supportive to being worried about how it will change their dynamic. Also, there's the theme of the unknown. The source of Sam's psychic boost might be a mystery, and exploring that mystery is part of the story. There can also be a theme of sacrifice, like Sam having to sacrifice normalcy to use this power for good.