In a Loki x Deadpool fanfic, Loki might initially seem like the more dominant character. He is a god, after all, with a vast array of magic powers at his disposal. He can manipulate minds, create illusions, and teleport. However, Deadpool doesn't play by the rules. His complete lack of fear and his ability to constantly regenerate from any injury mean that he can keep coming back no matter what Loki throws at him. So, while Loki has more traditional forms of power, Deadpool's unorthodox nature could make him equally, if not more, dominant in the long run. For example, if they were in a fight in a city, Loki might use his magic to try and subdue Deadpool, but Deadpool could just keep running around, causing chaos and disrupting Loki's plans.
One idea could be that Loki and Deadpool are forced to team up by some cosmic entity. Loki is initially annoyed by Deadpool's constant chatter and antics, but gradually comes to respect his unorthodox fighting style. Another plot could involve Deadpool getting transported to Asgard and causing chaos, with Loki having to either clean up his mess or use it to his advantage. Maybe they could also be on a quest to retrieve a powerful artifact that has been stolen and is being misused in the multiverse.
Deadpool became Deadpool through a series of complex and sometimes convoluted events in the comics. He was originally a mercenary named Wade Wilson, who underwent experimental treatments that gave him his unique powers and personality.
There is a loose link. The version of Deadpool in Wolverine Origins provided a starting point, but the standalone Deadpool movies developed his character and story in a more distinct and expanded way, deviating from the initial portrayal to create a more focused and engaging narrative.
It's a bit of a mixed bag. While there's a link, the portrayal of Deadpool in Wolverine Origins doesn't fully align with his later, more developed storyline. Some elements were changed or not fully explored.
Obviously, the main characters are the two Deadpools. They are both versions of the same character but with potentially different backstories and personalities in this graphic novel.