One possible plotline could be Naruto arriving in a universe where chakra doesn't exist, and he has to learn new forms of power. Another could be that he meets alternate versions of his friends with different personalities. For example, Sasuke could be a pacifist in that universe.
He could make allies with the local magic users if the universe he travels to has a magic system. They might be intrigued by his ninja abilities and see the potential in working together.
In this fanfiction scenario, Naruto could bring his ninja skills to the Def universe. He'd probably have to adapt to the new environment. For example, if the Def universe has different laws of physics, his usual jutsu might not work the same way. He might also learn new techniques from the Def universe and combine them with his own.
One interesting plotline could be Naruto arriving in an alternate universe where the Akatsuki are the heroes. He has to figure out how to navigate this new world where his former enemies are now revered.
He could meet alternate versions of his friends. For instance, an alternate Sasuke who has never left the village and is a strong ally from the start. This Sasuke could be more open and friendly, and together they could face the challenges of the new universe.
Some female ninjas who are intrigued by his different upbringing and abilities could be his allies. They might see him as an interesting novelty and someone who can bring new ideas to their world.
There could be a sidekick character, like a little alien creature named Zee. Zee might be small but is really smart and helps Percy out of many tricky situations during their travels.
In the 'naruto travels to a female ruled universe fanfic', Naruto's journey would be full of surprises. Firstly, the values of the society would be different. Things like honor and strength might be redefined according to the female - centered culture. He may have to deal with different gender roles as well. For instance, he could find that men are expected to play more supportive roles in combat or in the community. Also, the way ninjas are trained and organized could be very distinct from what he is used to in his own universe.
Well, he might join the Avengers. Imagine Harry using his magic skills alongside Iron Man's tech. It could be a really cool combination. He could use spells to enhance the team's defenses or help in battles in ways the regular Avengers couldn't. Maybe he'd have some clashes with Doctor Strange at first, since they both deal with magic, but then they'd probably end up working together.