In a 'Naruto Needs Help' fanfiction, Naruto could get help from unexpected sources. The tailed beasts themselves could come to his aid. Since Naruto has a connection with Kurama, the other tailed beasts might sense his distress and offer their power. Also, characters from other villages. For example, Killer Bee could teach Naruto some new techniques related to the tailed beasts' power, or Temari could use her wind techniques to assist in a battle where Naruto is outnumbered.
One possible plot could be Naruto facing a new and powerful enemy that he can't defeat alone. Maybe an ancient evil has been awakened and Naruto needs to seek help from old foes turned allies, like Gaara and Sasuke. He might also need to learn a new jutsu or power in order to stand a chance against this threat.
One possible story could be that Danny is facing a new and extremely powerful ghost. He needs help from his friends Tucker and Sam. Maybe they need to find a rare artifact to defeat this ghost. They could start by researching in the local library, looking through old ghost lore books. Tucker uses his tech skills to try and track down any leads on the artifact's location, while Sam uses her knowledge of the occult.
One common plot is Naruto having a really tough day in the village, facing more than the usual amount of ostracism, and then someone like Iruka or Hinata gives him a much - needed hug. Another plot could be Naruto coming back from a difficult mission and being comforted. Sometimes, it's about Naruto having a flashback of his lonely childhood and then getting a hug from a friend or mentor to show that he's not alone anymore.
Maybe Snape has a difficult spell he can't seem to master, and as much as he hates to admit it, Hermione's academic prowess makes her the best person to ask for help. He approaches her in a very snarky way, but she sees through his facade and decides to assist him. This could lead to an interesting dynamic where they start to respect each other more.
He could be in a situation where he's trapped in the Ghost Zone. His friends might have to figure out a way to get to him. They could use some of Tucker's new inventions, like a Ghost Zone - traversing vehicle. They'd face many challenges along the way, such as avoiding other dangerous ghosts.
In some Naruto fanfictions, ANBU could help Naruto by providing him with special training. They are highly skilled and could teach Naruto new jutsus or improve his existing ones. For example, they might help him master some advanced stealth techniques.
The conflict could be Snape's pride. He is a proud man and asking for help, especially from a student like Hermione, goes against his nature. So he constantly battles his own ego while Hermione has to deal with his snarky remarks.
Definitely Tony Stark (if he were still alive in the fanfiction). Tony has always been a mentor to Peter. His vast knowledge and resources could be invaluable in helping Peter deal with whatever problem he has. He could create new gadgets for Peter to use in case his omega situation requires special equipment.
In a fanfiction scenario, it's also likely that he discovers a new community of omega superheroes or mutants. This new community could teach him about his omega nature, its strengths and weaknesses. They could also help him develop new skills or powers that are unique to omegas, which would then help him in his fight against evil.