It could be 'Harry Potter'. In the series, there are many magical and unexpected things, and a toy - like object coming to life, like a spider jumping out, would fit right in with the magical world J.K. Rowling created.
In a horror - themed novel, it could be a sign of impending doom. For example, if it's a gothic horror novel, the toy spider jumping out might be the first sign of the supernatural forces at work, which would heighten the sense of fear and mystery for the characters and readers alike.
The 'Kraven's Last Hunt' is a classic. Kraven the Hunter, who has long been an adversary of Spider Man, decides to prove his superiority in a very extreme way. He hunts Spider Man, drugs him, and then buries him alive. It's a dark and intense story that really delves into the psychology of Kraven.