It could be Orochimaru. He might see Naruto's new form as an interesting experiment or a threat to his plans. He could try to capture Naruto to study her newfound female - related powers or use her in some dark jutsu.
Another plot could involve Naruto's relationships. As a female, her friendships with characters like Sakura and Ino might change. They could bond over more 'female - centric' things while still being ninjas. Also, her relationship with Sasuke could take on a different dynamic. Maybe there would be more of a romantic tension from the start, and she would have to navigate those feelings while still trying to bring Sasuke back to the village.
Naruto's character may develop more sensitivity. As a female, she might be more attuned to the feelings of others around her. This could enhance her relationships with her friends and comrades. Regarding Kurama, she might develop a deeper spiritual connection with it, as she explores her new identity. This could lead to her becoming a more well - rounded and powerful ninja.
Maybe in this fanfiction, Naruto as a female could develop a different kind of relationship with Sasuke. Since the dynamic between male - female friends can be distinct from male - male friendships, it could lead to new story arcs and character growth for both of them.
Well, for one, Naruto's self - confidence might develop differently. As a female, she may face different insecurities. For example, she might be more self - conscious about her appearance in a way male Naruto wasn't. But at the same time, she could also use her femininity as a strength, like using charm to get out of tricky situations during missions.
One possible interesting plot point could be how Naruto, as a female, copes with the new social dynamics in the ninja world. For example, she might face different expectations from her male counterparts. Another could be how her relationship with Kurama changes. Since Kurama is a powerful and somewhat unpredictable force, a female Naruto might interact with it in a more empathetic or different way compared to male Naruto.
The change to female could lead to a more competitive relationship in some aspects. Since they are now female, they might feel the need to prove themselves more in a male - dominated ninja world. This could add a new layer of tension to their relationship, but also a new form of respect as they see each other's efforts. They could be rivals not just in terms of power but also in terms of how they are perceived as female ninjas.
In this kind of fanfiction, there could be a lot of interesting plot developments. Maybe Naruto and the now - female Sasuke would have a different kind of relationship dynamic. Their interactions might be more about understanding each other from a new perspective. For example, Sasuke, as a female, could show more emotional vulnerability, which might make Naruto more protective of her. And their shared goals might be influenced by this new gender - changed situation.
The main characters are Naruto, Sasuke who is turned female by Mikoto, and Mikoto herself. Naruto is an important character as his relationship with Sasuke is central to the Naruto series. Now with Sasuke being female, their relationship will take on a new dimension. Mikoto is also a key character as she is the one who causes this change in Sasuke.
One idea could be that as females, they have a different dynamic in their friendship. Maybe they bond over more traditionally feminine interests while still having their ninja goals. For example, they could share a love for flower - arranging which is a contrast to their usual battle - focused activities.