I think the Destiny Hunter class has a good chance of being very powerful in a crossover. Hunters are known for their agility and stealth. In the Warframe universe, they could use their stealth to infiltrate Orokin facilities or sneak up on Sentients. They also have a wide range of powerful guns that could be modified with Warframe technology for even more destruction.
One possible plot twist could be the merging of Warframe's unique movement abilities, like bullet jumping, with Destiny's more traditional FPS movement. Imagine a Warframe character suddenly appearing in the Destiny universe and using their acrobatic skills to outmaneuver the enemies. Another could be the combination of Warframe's Orokin technology with Destiny's alien races. For example, the Vex could start using Orokin energy sources, leading to a whole new level of threat.
One idea could be that the Tenno from Warframe are summoned to the Naruto universe during a great war. They could use their advanced technology and unique abilities to help the ninja clans. For example, the Excalibur could use his Radial Javelin ability to clear out large groups of enemy ninjas, much like a powerful ninjutsu.
A Warframe crossover with the Star Wars universe would also be cool. Picture the Jedi or Sith facing off against the Warframes. The Force versus the Orokin technology - based powers of the Warframes could lead to some epic battles and interesting character interactions. Maybe a Sith Lord would be intrigued by the power of the Warframes and try to corrupt them for his own use.
Loki is often a popular choice. His ability to deceive and his stealth capabilities can create really interesting plotlines in crossovers. For example, if crossed over with a detective - themed universe, Loki could be the elusive criminal that the detective characters are trying to catch, using his Warframe skills to outwit them.
One idea could be to cross Excalibur with a popular fantasy universe like Middle - earth. Imagine Excalibur in the role of a ranger, using his swordsmanship and Warframe abilities to fight orcs and other dark forces. Another could be a crossover with the Star Wars universe, where Excalibur might be a Jedi - like figure, with his own unique powers and a lightsaber - like version of his sword.
The more serious characters in Naruto, like Sasuke, would have a different kind of interaction. If he met the Mesa Warframe, known for her precision shooting, he might be intrigued by her combat style. Sasuke could see the potential of combining his Sharingan - enhanced aim with Mesa's abilities. They might form an uneasy alliance at first, but as they face common enemies in the crossover, they would grow to respect and rely on each other.
One idea could be that Umbra gets transported to another universe where he has to team up with characters from a different game or story. He could use his unique abilities to overcome new challenges. For example, his combat skills and his connection to the Void could be really useful in a more magic - based crossover world.
The characters would likely have an initial period of confusion. The Warframe Tenno, being used to their own high - tech battles, might be startled by the more 'primitive' but still effective weapons of RWBY. Meanwhile, the RWBY characters could be in awe of the Warframes' advanced abilities. For example, when a Warframe uses teleportation, the RWBY team would be both amazed and a bit suspicious. Eventually, they would start to work together, with the Warframes teaching the RWBY characters about advanced combat tactics and the RWBY characters showing the Warframes the ins and outs of their world.
Another challenge is creating a plot that makes sense for both sets of fans. The story has to appeal to Destiny 2 fans as well as fans of the other game. If it's too focused on one side, the other group of fans might not enjoy it. For instance, if a crossover with The Elder Scrolls is too centered on Destiny 2 mechanics and doesn't incorporate enough of The Elder Scrolls' rich world - building, it could be a turn - off for Elder Scrolls fans.