Yes. The story draws from real - life situations that are full of family drama and turmoil. It shows how family members can be cruel to one another under certain circumstances, like in the case of the characters in 'Flowers in the Attic: The Origin'. The true story behind it probably inspired the author to write about such a disturbing yet captivating family dynamic.
One key element is the family's isolation. In the true story, as reflected in the book/movie, the family was likely cut off from the outside world, which allowed for the secrets and abuse to fester. Another element is the power struggle within the family, with the adults having control over the children's lives in a very unfair way.