Naruto might initially be in denial. He's so used to having Sakura around and believing that they have a future together. So when she leaves for Sasuke, he might think it's just a temporary thing or that she's been influenced by something or someone. But as time passes and he realizes it's real, he would be deeply hurt. He might also start to question his own self - worth, thinking that he wasn't good enough for Sakura. And he might even try to win her back at first, but then slowly come to accept the situation and focus on his other responsibilities like being a ninja and protecting the village.
She might be heartbroken. Sakura could initially be in shock and then fall into a deep sadness. She may blame herself for Naruto's leaving, thinking that she could have done something differently.
She could be heartbroken. Sakura has always loved Sasuke deeply, so his leaving for Naruto would be a huge blow to her. She might initially be in denial, not believing that Sasuke would choose Naruto over her.
One possible reason could be her long - standing and deep - rooted love for Sasuke. Since childhood, she has had strong feelings for him. Maybe in this fanfiction, she realizes that her feelings for Sasuke are unshakable and that she can't continue to be with Naruto while having such intense feelings for another.
The dynamic would be turned upside down. Sasuke would likely become more of an outcast or a loner, feeling rejected. Naruto would be in a difficult position, having to balance his friendship with Sasuke and his new relationship with Sakura. Sakura would be the catalyst for this change, and she would have to face the consequences of her actions, like dealing with the villagers' opinions and the potential backlash from Sasuke's supporters.
One reason could be that Naruto realizes his feelings for someone else and doesn't want to mislead Sakura. In some fanfictions, Naruto might discover that his true love is Hinata and so he steps away from Sakura to pursue a relationship with Hinata without causing any confusion for Sakura.
Maybe Naruto realizes that his feelings for Sakura are not as strong as he once thought. In the fanfiction, he could have met someone else or had an epiphany about his own emotions. He might leave Sakura to find his true self and explore different relationships.
If Sakura were to give Naruto a token made of sakura leaves as a symbol of their friendship, and then later break off all contact with him and leave the village, Naruto would be heartbroken every time he saw a sakura leaf. The once - positive association would become a painful reminder.
One possible fanfiction could be that Sakura, in a moment of great sacrifice, uses her chakra to turn into sakura leaves that Naruto has always associated with her beauty and kindness. But this transformation is a final goodbye as she is sacrificing herself to save the village. Naruto is heartbroken as he watches the sakura leaves scatter, feeling like he has lost a part of himself.
She may feel angry at first. Sakura is a strong - willed character. She might think that Naruto has made this decision without considering her feelings. In the fanfic, she could go on a rant about how he should have talked to her before making such a big decision.