Naruto could try to talk her out of it. He is a firm believer in the power of friendship and words. So, he would likely use his words to try and break whatever spell or wrong idea is in Sakura's head that made her want to kill him.
It could be due to a dark influence. Suppose she was under the influence of some dark magic or an evil force that made her lose her true self and turned her against Naruto. This could lead to her almost killing him in the fanfiction.
There could be. Fanfiction allows for a wide range of interpretations and alternate storylines. But it's a really extreme and disturbing concept considering the bonds that Naruto, Sakura, and Sasuke share in the official story. It would be a very different take on the characters, and most fans who love the original story would probably find it hard to accept.
One common theme is self - doubt. Naruto may doubt his worth as a ninja or a friend, feeling like he has let everyone down. Another theme is the burden of his past. All the hardships he has faced can pile up and seem overwhelming, pushing him towards self - destruction.
One possible reason could be a misunderstanding. Maybe Sakura is under the influence of some dark magic or mind - control in the fanfiction, which makes her lose her rational judgment and attack Naruto. Another reason might be a strong emotional outburst. For example, if she discovers something she believes Naruto has done wrong, but in fact it's a misinformation, and her anger gets the better of her, leading to her almost killing Naruto.
One popular 'naruto almost kills himself' fanfiction might be 'The Brink of Despair'. In it, Naruto faces extreme emotional turmoil after a major loss and comes dangerously close to self - harm. However, his friends' memories and his unwavering will to protect the village eventually pull him back from the edge.
One possible reason could be a misunderstanding. Maybe Sasuke is framed for something really bad, and Naruto, in his anger and sense of justice, lashes out without knowing the truth. For example, if there's a false rumor that Sasuke has attacked the village again, Naruto might be quick to act.
In such a fanfiction, one possible storyline could be that Sakura is under some dark magic or mind control which makes her turn against Naruto. Another could be a huge misunderstanding where she believes Naruto has done something unforgivable to her or their friends.
It's rather controversial. Naruto and Sakura are main characters in the Naruto series, and their relationship, while complex, is not one where fans would expect Sakura to kill Naruto. It goes against the general positive dynamic that the series has built between them.
Another character could come to his rescue. For instance, Sasuke might show up at the crucial moment. Despite their complex relationship, Sasuke still values Naruto as a friend or rival. He intervenes and stops Sakura from killing Naruto. Or perhaps Kakashi, Naruto's teacher, arrives in time. He uses his Sharingan or some other jutsu to neutralize Sakura's attack and save Naruto.