Definitely. Coyotes with mange are often in poor health and more likely to attack humans or other animals out of desperation or fear. Their weakened condition can also make them carry more diseases that pose a threat.
Yes, mange can be fatal for coyotes. If left untreated, it can severely weaken their immune system and cause various complications that may lead to death.
Yes, it could be true. Pitbulls are known for their strength and tenacity. If a pitbull was in a situation where it felt threatened by coyotes, it might fight back and be able to take on multiple coyotes. However, without more evidence, it's hard to be 100% certain.
I'm not sure specifically as I haven't read it. But generally, a graphic novel about coyotes could be about their lives in the wild, their behavior, or perhaps a fictional story where coyotes play a central role.