As of my knowledge, there's no indication that Kaley Cuoco is pregnant on 'Based on a True Story'. Usually, such details would be reported in entertainment news if it were a significant part of the show, but I haven't come across any such news.
The 'Kaley Cuoco True Story' could refer to many aspects of her life. It might be about her journey in the acting world, from her early start to her well - known roles like in 'The Big Bang Theory'. It could also involve her personal growth, relationships, and how she overcame challenges in Hollywood.