Well, one possible plot could be a character in the Naruto universe suddenly developing Six Eyes. This new power could disrupt the existing power balance. For example, they might be hunted by various ninja clans who either fear the power or want to use it for their own gains. Maybe this character has to go on a journey to learn how to control the Six Eyes and in the process, they meet some of the well - known Naruto characters like Naruto himself or Sasuke. They could form an alliance or have some conflicts depending on how the story unfolds.
In the fanfiction, the origin of Naruto having six eyes might be related to a special training or a forbidden jutsu. He could have stumbled upon an ancient training ground where he was exposed to some sort of energy or knowledge that granted him the six eyes. Or maybe he was forced to use a forbidden jutsu to save his friends during a critical battle, and as a side effect, he got the six eyes.
Well, it could make his combat style more versatile. He might be able to analyze his opponents' moves more precisely. With six eyes, he could have a wider field of vision, detecting attacks from more angles. Maybe he can use this new visual ability to anticipate his enemies' actions better and counter them with more effective jutsu combinations.
Toge Inumaki is important too. His special cursed speech ability makes him stand out. Also, the principal of the school, Masamichi Yaga, is likely to be important as he is in a position of authority and has an influence on Gojo and the other students. There could be other characters like the members of different clans that also play roles in the complex web of the story.