The Olympian council itself could be the antagonist if they are the ones forcing the marriage for their own political gain. They might not care about Artemis' wishes or Percy's attempts to stop it, and they use their power and influence to push the marriage forward.
A group of dark forces or minor gods could be the antagonists. They might believe that the union of Percy and Artemis would disrupt the balance in a way that benefits them. So, they engineer the situation where Percy is forced to marry Artemis, hoping to use the resulting chaos to their advantage. They would likely try to keep Percy and Artemis from finding a way out of the forced marriage.
It could be a powerful Titan who has escaped from Tartarus and blames Artemis for something in the past. So he's out to get her, and Percy has to stop him at all costs, even if it means his death.
A powerful Titan who has escaped from Tartarus could be the main antagonist. He might be seeking revenge on Artemis for her role in the previous battles against the Titans. This Titan could have new and terrifying powers that make him a formidable foe for Percy and Artemis.
A powerful Titan who has a grudge against both Percy and the Hunters of Artemis could be a great antagonist. Maybe he wants to use the power of the Hunters for his own evil purposes or destroy Percy to get revenge on the gods.
There could also be a group of rogue demigods who oppose the daughter of Artemis. They might be jealous of her powers or her connection to Artemis. They could try to sabotage her and Percy's quests and cause trouble for them at every turn.
Well, Percy is a resourceful character. In this fanfiction scenario, he could start by investigating the reasons behind being forced to marry Artemis. If it's some sort of plot by an enemy god, he'd work on uncovering it. He might also use his skills in combat and his connection to water to create some sort of diversion or escape plan if things get too tough. And he'd definitely have some internal conflict, given that Artemis is a virgin goddess and such a marriage goes against her nature too.
It could be a new demigod who has turned to the dark side. Jealous of Percy's popularity and Artemis' power, this demigod could try to create chaos in the high school and turn students against them.
A good antagonist could be a powerful and vengeful centaur. Centaurs are known for their knowledge and combat skills. This centaur could have a grudge against both Percy, perhaps because he defeated some of the centaur's friends in the past, and the Hunters of Artemis because they protect the forests that the centaur wants to claim for his own evil purposes.
One possible storyline could be Percy trying to find a way to break the forced marriage. He might seek the help of the gods who are sympathetic to Artemis' situation. Another could be Artemis using her wits and powers to resist the marriage while Percy supports her from the sidelines. Maybe there's a prophecy involved that the marriage is a part of but they find a loophole.
A great main antagonist could be a powerful Titan who has somehow escaped from Tartarus and is seeking revenge on the gods. He could target the Hunters of Artemis because they are loyal to Artemis, a goddess he has a grudge against, and Percy because of his connection to Poseidon.