It could also be related to personal relationships. Tsunade might have been hard on Naruto in a way that he felt was unjust. Perhaps she was overly critical of his unorthodox ninja techniques or his impulsive nature, and over time, this built up into hatred. Naruto, being someone who values respect and recognition, could have resented her for not seeing his potential in the way he wanted.
One possible reason could be a misunderstanding. Maybe Naruto overheard some false information about Jiraiya and Tsunade that made him think they had wronged him or someone he cared about. For example, if he heard they were involved in a plot that led to the death of a fellow villager, it could turn his feelings sour.
Perhaps Naruto blames them for some of the hardships he faced. Maybe he thinks that Jiraiya wasn't around enough when he needed a mentor, and Tsunade didn't do enough to support him in certain situations. This could lead to feelings of resentment and hatred in the context of the fanfiction.
One possible reason could be a misunderstanding. Maybe some false information was spread about Kushina that made Naruto believe she was a bad person. For example, if there were rumors that she abandoned him for some untrue reason, it might lead to his hatred.
It could be that Yugao has a connection to an enemy or a group that Naruto dislikes. This connection could make Naruto view her with suspicion and ultimately hatred. In some fanfiction scenarios, she could be unknowingly involved with a plot against Naruto or his village.
One possible reason could be the pressure associated with the Hokage title. Naruto has always been in the spotlight and being Hokage comes with a huge burden of responsibility. Maybe in the fanfiction, he resents how it restricts his freedom to just be himself and have adventures like he used to.
One possible reason could be that he feels burdened by the expectations associated with the Uzumaki clan. Maybe he doesn't like the constant attention or the pressure to live up to the clan's legacy.
One possible reason could be a misunderstanding. Maybe Naruto misinterprets some of Sasuke and Sakura's actions as being against him or the village. For example, Sasuke's quest for power might seem like a threat to Naruto, and he could misread Sakura's loyalty to Sasuke as a form of betrayal to their friendship.
One possible reason could be a misunderstanding. Maybe his team made a decision without consulting him, which made him feel left out and thus led to hatred. For example, if they took on a mission without him, Naruto, who values being part of the team, might feel betrayed.
Perhaps in this fanfiction's universe, Naruto's goals and ideals are completely different from Kakashi and Sakura's. Naruto may be aiming for a more radical change in the ninja world, while Kakashi and Sakura are more conservative. Their differences could lead to Naruto developing a sense of hatred towards them as they constantly oppose his ideas.
In the fanfiction, it could be that Naruto has had some personal negative experiences with Uchiha clan members. He might have witnessed some Uchiha using their power to bully or oppress others. Naruto, being the kind - hearted person he is, would not tolerate such behavior and thus develop a hatred for the clan as a whole. This could also be related to the Uchiha's reputation for being a bit of an outcast clan, and Naruto might see them as not fitting into the harmonious village life he envisions.