Perhaps there could be a story where Agent Venom is framed for a crime he didn't commit, and Spiderman is the only one who believes in his innocence. They then go on a journey to clear Agent Venom's name while also uncovering a bigger conspiracy in the city. Along the way, they have to fight off other villains who are after them.
In a Venom x Spiderman fanfiction, a plot could involve Venom and Spiderman having to work together to stop a symbiote invasion from another dimension. The symbiotes from this other dimension are more aggressive and have different abilities. Spiderman has to use his intelligence and web - slinging skills, while Venom uses his brute strength and symbiotic powers. Along the way, they could start to understand each other better, and Venom could learn some of Spiderman's sense of responsibility. This would be a great opportunity for character development for both of them.
One idea could be that Venom and Spider - Man are forced to team up against a new symbiote villain that is far more powerful and malevolent. This new symbiote could be controlling innocent people, and Spider - Man and Venom have to find a way to stop it without harming the hosts.
One idea could be exploring how the relationship between Spiderman and Venom changes during the pregnancy. Maybe they become more protective of each other.
One plot idea could be that the female Venom has a split personality. One side is attracted to Spiderman, while the other side is a more menacing villain. This creates an internal struggle within her as she interacts with Spiderman. Another idea is that she and Spiderman have to team up against a common enemy, like a new symbiote that is causing chaos in the city. As they work together, they start to understand each other more and a romantic tension builds.
One idea could be that She - Venom has a unique connection to Spider - Man's spider - sense. Maybe her symbiotic abilities interfere with it in unexpected ways, leading to some comical or dangerous situations as Spider - Man tries to adapt. Another could be a story where She - Venom and Spider - Man have to team up to stop a new super - villain who is immune to the regular attacks of both of them, forcing them to combine their powers in creative ways.
One plot idea could be that Agent Venom is initially sent to spy on Peter Parker, thinking he might be a threat. But as he gets to know Peter better, he realizes that they could be great allies against a common enemy, like a new super - villain in the city.
The Green Goblin could be a great main antagonist. He could be jealous of the new team - up between Spiderman and Agent Venom and see them as a threat to his own plans for the city. So he devises a series of traps and attacks to try and take them down.
One idea could be that the OC is a scientist who accidentally creates a device that can disrupt Spiderman's powers. This leads to a series of events where they have to work together to fix it while also facing off against a new villain who wants to use the device for evil. Another could be the OC is a new superhero in training and Spiderman becomes their mentor, and they develop a close bond as they fight crime together.
One plot idea could be that Spiderman gets transported into the Overwatch universe. He has to team up with the Overwatch heroes to stop a villain who has technology that can disrupt both universes. For example, Doomfist might be interested in using this technology to gain more power, and Spiderman's agility and unique powers would be useful in the fight.
One idea could be that The Vulture has a change of heart after Spiderman saves his life in a dangerous situation. He then decides to use his knowledge of technology to help Spiderman secretly against other villains. Another could be a story where they are forced to team up in an alternate dimension where they are the only ones who can stop a greater threat. A third idea is that The Vulture's daughter is in danger and Spiderman has to help him save her, which then leads to a strange alliance between them.