Maybe the daughters or sons of the original 'A' could be involved in some sort of revenge plot. They might think that the original liars wronged their parents in some way and decide to make the new generation pay. This would create a lot of tension and drama as the new liars try to figure out who is after them and why.
Another plot could be centered around a new set of rules at their school. The new generation has to deal with strict regulations that seem to be targeting them specifically. As they dig deeper, they find out that there is a connection to the past events of the original Pretty Little Liars. They then have to fight against the system while also dealing with their own personal issues and the mystery of who is behind these new rules.
One idea could be that the new generation of liars discovers a long - hidden secret about their parents' time as liars that starts to put them in danger. For example, an old enemy from the past resurfaces, thinking the kids know something valuable.
Well, a great plot could be that Caleb finds a strange encrypted file on his computer that seems to lead to a hidden treasure in Rosewood. As he tries to decipher it, he has to team up with some unexpected characters from the show. Maybe he also has a vision or a strange dream that leads him to believe there's something supernatural going on in the town related to the file. Also, he could get into a situation where he has to choose between his loyalty to his friends and his own personal gain from the treasure.
One idea could be exploring the backstories of the minor characters in more detail. For example, what was the life of Jenna before she became blind? Another idea is to create an alternate universe where the 'A' mystery was solved much earlier, and how the characters' lives would be different. Maybe they would all be closer friends and focus more on normal high school stuff like prom and college applications.
One idea could be Aria exploring a new art form in Paris for a semester and getting involved in a mystery there related to the 'A' games. Maybe she meets a mysterious artist who seems to know more about her past than she does.
One idea could be Haleb going on a secret adventure together away from all the drama in Rosewood. They discover a hidden place that has a connection to one of the mysteries in town. Another could be them dealing with family issues together and growing even closer through it.
One idea could be that one of the main characters discovers she's pregnant and has to keep it a secret from the 'A' threats. She might be afraid that 'A' will use the pregnancy against her or her friends.
One idea could be that Paige and Emily go on a road trip together to discover more about their relationship away from the drama of Rosewood. They could encounter various challenges along the way that test their love and loyalty to each other.
Another plot could be Mike developing a relationship with one of the new characters in town. This new relationship could be complicated by the secrets and drama that always seem to surround Rosewood. For example, the new character could be related to one of the 'A' suspects, and Mike has to figure out if he can trust them.
One idea could be exploring a different backstory for one of the main characters. For example, delving deeper into Alison's life before she disappeared. Maybe she had a secret friendship with someone outside of the main group that no one knew about. This could add a whole new layer of mystery to the story.
One idea could be exploring the family secrets of the Liars' parents before they were born. Maybe there was some kind of feud or alliance between the families that the Liars are unaware of. Another could be a story where one of the Liars discovers they have a long - lost relative who has a connection to 'A'. For example, a cousin who has been watching over them all this time.