There are many great novels in it. '1984' by George Orwell is likely to be on the list. It depicts a dystopian future where the government has extreme control over people's lives. 'The Great Gatsby' by F. Scott Fitzgerald is also a strong contender. It shows the decadence and dreams of the Jazz Age through the character of Jay Gatsby.
The Guardian Top 100 Novels would surely include works like 'Moby - Dick' by Herman Melville. This novel tells the story of Captain Ahab's obsessive quest to hunt down the white whale. It's not just an adventure story but also a deep exploration of human nature, fate, and the power of the sea. There are also modern works that might be in there, but these older classics are some of the most likely candidates.