In real - life, human estrus is not as overt as in some science - fiction concepts. In science fiction, it can be highly exaggerated or modified for the sake of the story. For example, in a sci - fi story, the estrus might be linked to some special power or ability that a character gets during that time.
Science - fiction often takes the concept of human estrus and twists it in unique ways. In real life, the estrus cycle is mainly related to reproduction, but in science - fiction universes, it could be related to things like interspecies mating. Imagine a story where humans can mate with an alien species during a specific 'estrus - like' phase. This is far from the reality of human biology where our estrus is not designed for such cross - species interactions.