Meep is significant in American Horror Story as he embodies the concept of the 'freak' in the freak show setting. He is a symbol of those who are marginalized and mistreated because of their differences. His story arc allows the show to explore themes of acceptance, discrimination, and the human condition. His character also adds an element of pathos and tragedy, making the audience feel sympathy for him and, by extension, for all those in society who are pushed to the fringes.
The significance of Meep is that he represents the outcasts. He shows the hardships they face.