Maybe a rogue ninja who has a grudge against Naruto. This ninja sees Millet as an easy target since Millet is Naruto's servant. They could try to kidnap Millet to force Naruto into a trap. It could be a ninja who was once defeated by Naruto and now wants revenge in a more devious way.
There's also the possibility of a new character being the main antagonist. This character could be jealous of Naruto's growing influence and power. They notice Millet's loyalty to Naruto and decide to turn Millet against Naruto by using some dark magic or false information. This would create a lot of internal conflict for Millet and put their relationship with Naruto to the test.
It could be someone from the Akatsuki. They are always causing trouble in the Naruto universe. Since Naruto is important, they might target Millet to get to him. For example, Sasori could be interested in Millet's possible connection to Naruto, thinking he can use Millet to get some information about Naruto or use them as a bait.
Well, one possible plot development could be that Millet starts off as an inexperienced servant but gradually learns valuable skills from Naruto. Maybe Naruto teaches Millet some ninja techniques, which in turn helps Millet become more confident and useful in their adventures together.
It could be someone from the Naruto universe who doesn't like Naruto's newfound fascination with Aku. For example, Danzo might see Naruto's interest in Aku as a threat to the stability of the village and try to stop Naruto from further exploring Aku - related things. So, Danzo could be the main antagonist in this case.
Sasuke could potentially be an antagonist. With Naruto having the Rinnegan, Sasuke might see him as a threat to his own power and goals. This could lead to a new rivalry between them, different from their previous one.
Maybe a new character could be introduced as the main antagonist. This character could be from a hidden village that has been secretly observing Naruto's growth. They realize his potential as a weapon and plan to steal his power or use him to start a war against other villages.
Krampus himself could be the main antagonist. Since he is a figure known for punishing the naughty, his actions in the Naruto world might be seen as unjust. He could be going after ninjas without really understanding their motives, causing a lot of trouble for the main characters.
It could be a rogue ninja who also has somehow acquired bankai - like powers. This antagonist might be jealous of Naruto's newfound abilities and wants to prove that he is the stronger one. So he starts causing chaos in the ninja world, challenging Naruto at every turn.
It could be a rogue ninja who wants to disrupt Naruto's business to gain power. Maybe he's jealous of Naruto's success and popularity in the business world. He could try to steal Naruto's business secrets or sabotage his operations.
It could be a rogue Kumo ninja who is jealous of Naruto's power and wants to prove himself by defeating Naruto. This ninja might have some dark secrets and a grudge against Kumo as well.
It could be Orochimaru. He's always been interested in immortality and reanimation techniques. Maybe he reanimates Naruto for some evil purpose, like using Naruto's power to take over the ninja world.
Maybe it's a ninja who has also been affected by Anodite magic but has turned to the dark side. This ninja could be jealous of Naruto's new powers and want to take them for himself. He would use his knowledge of both ninja techniques and Anodite powers to try and defeat Naruto.