Another reason might be related to some kind of spiritual or mythical connection. In certain mythologies, there are beings that can transform between human and animal forms. She could be related to such a being, and due to some trigger, like reaching a certain age or entering a specific place, she turns into a cat.
Well, it might be due to a powerful magical artifact. She could have accidentally touched or used an enchanted item that had the power to turn humans into animals, like a cursed amulet. Or, in a more spiritual sense, it could be a connection to a spirit world where cats are guardians and she has been chosen to take on that form for a special mission. There could also be a deal made with a supernatural entity that she has to fulfill, and the transformation is part of the deal.
Maybe it's a curse. Some evil magic might have been cast upon her, turning her into a cat against her will.
In some stories, it could be a curse. Maybe the boy's family angered a powerful being, and as a punishment, the boy is turned into a girl. This then sets up a story of trying to break the curse and restore his original form, which often involves a long and difficult journey filled with challenges.
In some fictional stories, a curse can also be the cause. Maybe an evil witch or wizard put a curse on the man because of some past conflict or just for their own malicious purposes.
In some fictional stories, scientific experiments gone wrong might lead to such a change. Maybe a scientist was trying to develop a new gene - editing technique and something unexpected happened to the girl who was part of the experiment.
In some stories, the forest or a special place with strong natural magic can be the cause. The girl might unknowingly step into a place where the magic is so concentrated that it changes her form. This could be a place that has been untouched for centuries and has its own will to transform those who enter it into something more in tune with nature, like a cat.
It could be due to a curse. Maybe someone with malicious intent put a curse on Ash that turned him into a girl.
One reason could be magic. Like in fairy tales, a magical spell might be cast on the girl accidentally or on purpose by a wizard or a magical creature. Another reason could be a scientific experiment gone wrong. Maybe she was part of an experiment that aimed to test some new genetic or hormonal treatment and it had unexpected results. Also, in some fictional worlds, a deal with a supernatural being might lead to such a transformation, for example, making a deal with a devilish figure who twists the terms.
In some stories, it could be due to a scientific experiment gone wrong. Maybe he was part of some research on gender - related hormones or gene manipulation and things didn't go as planned, resulting in his transformation into a sissy girl. This type of plot allows for exploration of the consequences of scientific overreach. Another possibility is that it's a psychological journey where the husband has some suppressed desires or traumas related to his gender identity, and through some event in the story, these come to the surface and manifest as a physical transformation, leading to his new state as a sissy girl.
Well, in some stories, it could be a family curse that has been passed down through generations. Maybe her ancestors made a deal with dark forces long ago and as a result, she is doomed to turn into a werewolf. Also, it could be related to a place. For example, if she lives in an area that has a strong connection to werewolf lore, the energy of the land could somehow trigger the transformation. And of course, as mentioned before, a werewolf bite is a classic cause.