The relationship between Issei and Sasuke would be very different. Sasuke, used to Naruto's determination to bring him back, would now face Issei. Issei might not have the same emotional connection to Sasuke as Naruto did. Instead, he could be more interested in Sasuke's power. With Sakura, Issei's more flirty nature could make her either annoyed or intrigued, quite unlike Naruto's one - sided love for her.
If Issei replaces Naruto, the relationship with the village elders would be altered. Naruto was seen as a troublemaker but also a potential savior. Issei, with his different background and abilities, would be an enigma to them. They might be more suspicious of him at first. And in terms of his relationships with other ninja, like Kakashi, Kakashi would have to adjust to Issei's fighting style and personality. Issei may not respond to Kakashi's teachings in the same way Naruto did, leading to a different dynamic in their mentorship.
The relationships in the story would change significantly. Issei's presence instead of Naruto would mean different interactions with the Akatsuki. The Akatsuki might view Issei as a new and unknown threat or opportunity. In his relationships with the other Jinchuriki, Issei would not have the same shared experiences as Naruto. He might approach them with his own motives based on his Devil - related knowledge. Also, his relationships with the various ninja clans in the village would be different. For example, the Hyuga clan might be more cautious around Issei compared to Naruto due to his foreign nature and powers.
In a fanfiction where Issei turns into a dragon, his relationships would be in flux. His relationship with his mentors or those he looks up to might change as they now see him as a different kind of being. They might treat him with more caution or more respect depending on how they view dragons. His friendships with his peers would also be altered. Some might see him as a weapon to be used in their battles or struggles, while others would see him as a friend in need of support. Romantically, if he had feelings for someone, that person would have to deal with the fact that Issei is no longer fully human. There could be jealousy from others who might want to be with the powerful dragon - Issei, or there could be newfound admiration from those who previously overlooked him.
With his female friends, there could be a shift in the dynamic as well. They might be more open with him now that he's a girl, sharing secrets and experiences that they previously wouldn't have. He could also become more involved in 'girl - only' activities, strengthening those friendships in new ways.
Naruto's relationships would experience significant shifts. With his friends, they would need to be more patient and creative in their communication. For example, Shikamaru, who is usually laid - back, would have to be more active in ensuring Naruto is included in conversations. Naruto's relationship with the Hokage would also be different. The Hokage would need to find new ways to give Naruto missions and communicate orders. In his romantic relationships, like with a potential partner, there would be a whole new dynamic. The partner would need to be understanding and learn to communicate in a way that suits Naruto's deafness, which could lead to a deeper and more empathetic connection.
His relationship with Sasuke would likely become more of a partnership. As Hokage, Naruto would need Sasuke's skills and knowledge to protect the village. They would probably have regular meetings to discuss security and other important matters.
His friends in Team 7, Kakashi included, would be deeply concerned. They would try to figure out what made Naruto change. However, Naruto's coldness would make communication difficult. He might distance himself from them, seeing their attempts as interference. His relationships with the villagers would also change. People who once looked up to him might now be afraid of him, as his cold demeanor is a far cry from the hero they knew.
Well, Naruto's relationships would change significantly. For instance, his relationship with his sensei, Kakashi, could shift. Kakashi would become more of a mentor in a different way, guiding Naruto through this difficult time. With his peers, they would no longer see him as just the powerful ninja he once was. Some might pity him at first, but Naruto's positive attitude could turn that pity into respect. And his relationship with the village as a whole would change too. He would become more of an inspiration, a symbol of perseverance in the face of adversity.
Naruto's relationship with his students, if he has any as a Jounin, would be very important. He would be a mentor figure. He would have to be strict but also kind, just like Kakashi was to him. He would pass on his values and ninja techniques. His relationship with the Hokage would also be different. He would be closer to being an equal, having more say in important decisions regarding the village's security and future.
His relationship with Sasuke would be very different. Sasuke might see Naruto as a threat at first, given the power of the Juubi. But eventually, they could come to an understanding. Naruto would still want to protect Sasuke, and Sasuke might realize that Naruto's intentions are pure even in his Juubi form.
His relationship with Sasuke could be affected. Sasuke might feel a sense of guilt or responsibility, especially if he had something to do with Naruto's condition. He could become more protective of Naruto, which would be a big change in their dynamic. Naruto, on the other hand, might initially be a bit hesitant to rely on Sasuke, but as time goes on, they could grow closer in a new way.
His relationship with Sasuke might become more complex. Sasuke, who has always been somewhat cold - natured, could be either drawn to Naruto's fiery energy or feel threatened by it. Sakura might be more cautious around him at first, afraid of getting burned. But as she realizes Naruto's good heart beneath the fire, she could become more protective of him.