One possible plot could be Peter struggling to keep his identity as Spider - Man a secret while also dealing with the challenges of Tourettes. For example, he might have to be extra careful during battles so that his tics don't give him away.
Perhaps the story could focus on how his friends and family react to his condition. Maybe Aunt May is trying to find the best ways to support him, while his friends at school are either very understanding or, unfortunately, some might be mean about it at first. And all of this while he still has his superhero duties.
The plot could also involve Peter using his scientific knowledge to try and find a way to manage his Tourettes better. He might experiment with different treatments or therapies, and this journey could be intertwined with his adventures as Spider - Man. For instance, he could meet some villains or characters who either help or hinder his search for a solution.
One possible plot could be that Peter has to deal with the physical pain and limitations of the broken leg while also trying to protect his secret identity. Maybe he has to come up with excuses for not being able to do certain things at school or with his friends. For example, he can't participate in gym class. And he has to be extra careful when changing into his Spider - Man suit so that no one sees his injury.
Well, one possibility could be that Peter Parker discovers he has a baby through some sort of strange situation. Maybe an old enemy left the baby at his doorstep as a way to get revenge, making his life even more complicated as he tries to balance being Spider - Man and taking care of a new - born.
Well, Fanfiction.net could also be a place to look. However, the tagging system there might not be as precise as AO3. You may need to dig a bit deeper. Maybe start by looking in the Spider - Man section and then search for any mentions of Tourettes within those stories.
One possible plot could be that Peter, after some tragic event that makes him lose faith in the justice system and superhero code, decides to take matters into his own hands in a more extreme way and becomes an assassin. He might target those who he believes are getting away with crimes that the law can't touch.
Maybe in this fanfiction, Peter's mutation into Spider is caused by some new and experimental Oscorp technology. The process is different from how he originally got his powers. As he mutates, he starts to lose some of his human memories and instincts, becoming more primal like a spider. His relationship with Aunt May would become very strained as she tries to understand what's happening to her nephew. Meanwhile, he has to face off against new enemies that are specifically attracted to his new spider - like form, thinking he's some kind of new prey or threat in the city.
One possible plot could be that Peter has lost his home due to some financial difficulties or perhaps after a villain attack destroys his place. He has to use his Spider - Man skills to survive on the streets. He might start by finding safe places to sleep at night, like on rooftops where he can also keep an eye out for trouble. Maybe he befriends some street kids and protects them from local thugs, all while trying to keep his identity a secret.
In a 'Peter Parker Funeral' fanfiction, the story might start with the discovery of Peter's death. It could be due to a powerful villain finally getting the upper hand. His Aunt May is heartbroken. The funeral could be a very private affair, with only his closest friends and family. But as the news spreads, the whole city starts to remember Spider - Man's deeds. There could be a lot of flashbacks in the fanfiction, showing how Peter grew into the hero he was.
One possible plot could be that Peter Parker is experimented on by some villain who wants to create chaos. The experiment goes wrong and it starts to mess with his mind, turning him into a Joker - like figure. He then starts to cause mayhem in New York City, using his spider - powers in ways that are more for destruction and amusement rather than heroism. His friends and family are shocked and try to figure out what happened to him and how to bring him back to his normal self.
One possible plot could be that Peter discovers he has Asgardian blood through some magical accident. He then starts to have visions of Asgard and is eventually drawn there. Once in Asgard, he has to prove himself worthy, just like Thor did with Mjolnir, but with his own unique set of skills as Spider - Man.
Well, it could be about Peter Parker getting trapped in subspace while on a mission. He might encounter strange entities there that he has to outwit to find his way back. Maybe he discovers some new powers or abilities while in subspace that help him in future battles in the normal world.