Well, it can be a tricky situation. You could try to calm the situation down. If her friends are upset, you might step in as a mediator. Maybe find a time when everyone is calm to talk it out and help your wife understand the importance of respecting others' stories, especially when drunk. And also, it's important to support your wife in making amends if that's what's needed.
First, make sure she is safe and comfortable. When she sobers up, have an honest conversation with her about how her actions might have affected her friends. Encourage her to apologize if necessary.
In this situation, it's important to approach it with understanding and patience. Since alcohol can sometimes make people act out of character. When your wife is sober, sit her down and gently explain how her actions while drunk may have caused discomfort or harm to her friends. Suggest that she reach out to them to clear the air. It could also be a good opportunity to have a broader conversation about appropriate behavior when drinking, and how to be more conscious of the feelings of those around her.