If Naruto goes back and his parents are alive, his relationship with them would be a whole new aspect. He would have a family bond that he never had in the original timeline. His father could train him from a young age, and his mother would give him the love and care he always craved. This would also affect how he interacts with others in the village as he now has a different family status.
With his friends like Sakura and Kakashi, things would also change. Naruto might be more confident and less of a prankster as he has the knowledge of the future. Sakura could see a more mature Naruto and their friendship could develop in a new way. Kakashi would also notice the change in Naruto and might start to rely on him more in different situations.
His relationship with Sasuke would be very different. If Naruto stops the Uchiha massacre, Sasuke may not have the intense hatred he had in the original story. They could grow up as friends without the need for Naruto to constantly chase after Sasuke to bring him back.