Definitely. There's 'Uncle Tom's Cabin' by Harriet Beecher Stowe. It had a huge impact on the view of slavery in America. 'The Scarlet Letter' by Nathaniel Hawthorne is also an epic in a sense, exploring themes of sin and redemption in Puritan society. And of course, 'For Whom the Bell Tolls' by Ernest Hemingway, set during the Spanish Civil War but with strong American elements in its themes and characters.
Sure. 'Moby - Dick' by Herman Melville is a well - known one. It's about Captain Ahab's obsessive hunt for the white whale. Another is 'The Grapes of Wrath' by John Steinbeck, which tells the story of the Joad family during the Great Depression. And 'Gone with the Wind' by Margaret Mitchell, set during the American Civil War and Reconstruction era.