One possible intriguing storyline could be the characters from Attack on Titan somehow ending up in the One Piece world. For example, Eren could use his Titan powers in the middle of the Grand Line, causing chaos among the pirates and marines alike. Another idea is that the Straw Hat crew might find themselves in the walls of Paradis Island and have to deal with the Titans while also trying to find a way back to their own world. Maybe Luffy would try to befriend some of the Survey Corps members, like he does with most people he meets.
A really cool plot could be that some of the Attack on Titan characters gain superpowers from the Marvel universe. For example, Mikasa could get some sort of enhanced combat abilities like Black Widow's training but on steroids. And the Survey Corps could learn new technology from Tony Stark to better fight the Titans. Also, Loki could play a devious role in the crossover, causing chaos between the two worlds by manipulating both sides.
Luffy would probably be really excited to meet the Survey Corps. He'd see them as cool warriors and want to team up right away. He might even try to convince them to join his crew. Eren, on the other hand, would be a bit more suspicious. He's used to a world full of danger and betrayal, so he might not trust the Straw Hat crew immediately. But as he sees their loyalty to each other, he could start to warm up to them.
Well, one of the most interesting plot twists could be a character that was thought to be on the side of the humans actually being a secret agent for the Titans all along. This would completely change the dynamic of the story and the relationships between the characters.
A great storyline might involve a fusion of the two worlds' mechanics. For example, the Velvet Room from Persona could have some connection to Joker's world. The Igor-like figure could offer Joker and his friends some new kind of power or knowledge that they use to combat a common foe. Or perhaps the Persona characters learn about Joker's Metaverse Navigator and try to replicate it in their world, which leads to all sorts of unforeseen consequences and adventures.
Often, there are fanfictions where the worlds of Fairy Tail and One Piece start to merge. The islands in the One Piece world might start to have magical properties and the Fairy Tail guild could have to deal with the chaos of the pirates suddenly showing up in their world. This can lead to some really interesting character interactions, like Erza trying to discipline Zoro or Lucy befriending Nami and sharing their knowledge about different types of treasures.
The cultural clash. The Marvel heroes come from a world with a different set of values compared to the more survival - based world of Attack on Titan. Seeing how they interact and try to understand each other's motives would be really engaging. For example, Steve Rogers might try to instill his sense of justice and freedom in the characters of Attack on Titan, while they might show him the harsh realities of their world.
Another could be a time - travel scenario where Naruto goes back in time and meets Rikudou Sennin. They then team up to prevent a great evil from ever arising in the first place. This would allow for a lot of character development and exploration of the Naruto universe's history.
One of the most interesting storylines could be the interaction between the different species in Mass Effect and those from Stargate. For example, how would the Asari react to the Goa'uld? The Asari are a long - lived, biotic - using species in Mass Effect, while the Goa'uld are parasitic snake - like beings in Stargate. Another cool idea is the technology exchange. The Mass Effect universe has advanced biotic and cybernetic technology, and Stargate has its own unique wormhole - based travel and Ancient technology. A fanfiction could explore how these technologies might be combined or used against each other. Also, the cultural clashes would be fascinating. The different races in Mass Effect have their own moral and ethical codes, and the same goes for the races in Stargate. How would they deal with each other's values?
One interesting storyline could be Naruto using the Sharingan to enhance his combat skills in a new and unexpected way. For example, he might combine his Rasengan with Sharingan - powered genjutsu to create a more powerful and deceptive attack.
A crossover involving a shared enemy. Maybe a new alien race that is a threat to both universes emerges. The combined forces of Babylon 5 and Star Trek would have to pool their resources. The Starfleet officers could share their scientific knowledge to analyze the new threat, while the Babylon 5 personnel could offer their street - smart combat and negotiation skills developed from their own experiences in the often - tumultuous Babylon 5 station.