The plot could involve Naruto using his ninja skills in the Monster Hunter universe. For example, his shadow clone jutsu could be used to distract monsters while he attacks from a different angle. Or he could use his chakra to enhance his Monster Hunter weapons. There could also be a story where Naruto teams up with the local Monster Hunters to take on a particularly powerful monster that is threatening the land.
One possible plot could be that Naruto, already a powerful ninja in his own world, discovers a portal to the Monster Hunter world. In this new world, he is intrigued by the concept of hunting monsters. He starts off as a novice, learning about the different types of monsters, their habitats, and the tools used to hunt them. As he progresses, he combines his ninja abilities with Monster Hunter techniques. He might face challenges like being shunned by some of the traditional Monster Hunters at first because he is different. But eventually, through his determination and unique skills, he earns their respect and becomes a great Monster Hunter in that world, all while trying to find a way back to his own world.
Maybe Naruto is transported to the Monster Hunter world and has to learn the ways of a Monster Hunter to survive.