A plot twist could be that Naruto receives the Mangekyou Sharingan from Sasuke in a self - sacrificing moment. Sasuke, realizing the true potential of Naruto's power combined with the Sharingan, decides to transfer his Mangekyou Sharingan to Naruto. This would create a whole new dynamic in their relationship. Naruto would then have to master the abilities of the Sharingan quickly to face an impending and powerful threat to the Hidden Leaf Village.
One possible plot twist could be that Naruto's new Mangekyou Sharingan gives him the ability to access a new form of Sage Mode. Since the Sharingan has unique powers and Sage Mode is Naruto's own power, their combination might create something unexpected. For example, he could use the Sharingan to better target his Sage chakra, making his attacks more precise and powerful.
One creative plot twist could be a character who was thought to be a normal ninja suddenly reveals they have a Mangekyou Sharingan with a unique power that changes the whole power dynamic in the story. For example, a side character who has been helping the main character all along, but then uses their Mangekyou Sharingan to stop an impending doom that no one else could. Another could be that the Mangekyou Sharingan has the ability to swap the powers of other ninjas, creating chaos and new alliances.
The plot could involve some sort of time - travel or alternate dimension scenario. Naruto could be sent to a parallel world where the Uchiha clan was never massacred. There, he befriends the Uchiha and learns their ways. Eventually, he earns the right to receive the Eternal Mangekyou Sharingan through his deeds and his strong bond with the clan. With this new power, he has to find a way to return to his own world and use it to protect his friends and village from a new, greater threat.
One possible plot twist could be that Naruto gains the Mangekyou Sharingan in a moment of extreme emotional turmoil, like seeing Sasuke in a life - threatening situation. This new power might make him an outcast in Konoha at first, as the Sharingan is a symbol of the Uchiha. Another twist could be that the Mangekyou Sharingan has some unforeseen side effects on Naruto's chakra system, making it difficult for him to control his normal jutsu. It could also lead to a power struggle within the village as some might fear Naruto's new - found power.
The character with the Mangekyou Sharingan might lose their eyesight due to overuse in the new and unfamiliar world of the crossover, but then gain a new form of power that is related to the crossover world. Maybe they lose their Sharingan sight but gain the ability to see magic auras or something similar. This would be a huge twist for both the character and the readers.
Another plot twist could be that Naruto getting the Sharingan is part of a much larger conspiracy. The Akatsuki might be behind it, trying to create a super - powerful being that they can control. So Naruto has to figure out who's behind this while also dealing with the new power. He might find that there are some hidden motives among his own allies as well, which would really shake up the story.
In such a fanfiction, one possible plot could be that Naruto acquires the Mangekyou Sharingan through some kind of magical or experimental accident. Maybe a powerful enemy uses a jutsu that backfires and transfers the Sharingan to Naruto. Then Naruto has to learn to control its power while also facing the prejudice from those who fear the Sharingan's abilities.
One possible plot twist could be that Ichigo struggles to control the Sharingan at first. Since he's not from the Naruto universe originally, the sudden addition of the Sharingan's powers might be overwhelming. He might accidentally activate it during battles in the Bleach world and it could give him an edge in seeing his opponents' moves more clearly, but also make him a target as it's an unknown power in his world.
Perhaps in the fanfiction, Naruto discovers a hidden connection between his Uzumaki heritage and the Sharingan. This newfound knowledge, combined with a great battle against a powerful villain, causes the Mangekyou Sharingan to awaken. It could also involve some sort of ancient prophecy or power that was long forgotten, and Naruto is the key to unlocking it which leads to the awakening of his Mangekyou Sharingan.
One possible plot twist could be that Naruto Namikaze, having the Sharingan, discovers a hidden connection between the Uzumaki and Uchiha clans that was long forgotten. This connection might give him unique powers or abilities that no one expected.